Millions of tickets were sold in 44 U-S states, with the draw taking place in Florida. The winners overcame odds of 1-in-292-million, but have yet to come forward.
19 previous draws produced no winners -- rolling the U-S Powerball jackpot into a total of 1.6-billion dollars.
The amount will be split equally between three, still officially unknown, ticket-holders -- who are believed to have lottery tickets purchased in the states of Tennessee, California and Florida.
Rebecca Hargrove is the president of the Tennessee Lottery Corporation - which is responsible for operating the lottery in that state. She says the winners would benefit from some financial advice.
"Our advice to whoever has that ticket is to make sure you sign the back of it, because the back of the ticket signature is a bearer instrument, so if you sign it you know it's yours. I'd suggest you get financial advice from someone you knew before you won. There are big tax consequences on whether you take the annuity or the lump sum, so make sure you check with somebody to make sure you take what's best for you. It makes no difference to us, it's the same either way. Get advice, sign the ticket and enjoy it."
Ms Hargrove's advice comes after groups of people descended on the venues where the winning tickets were sold.
There was frenzy in Chino Hills, California, with crowds cheering outside a Seven-Eleven convenience store.
Local resident Claudia Gonzalez couldn't contain her excitement.
"I'm out here because it's exciting to know that somebody from our little city won. It's so exciting. I'm excitement for them and I don't even know who it is!"
Each of the stores will also receive a bonus payment from lottery authorities.
The California Seven-Eleven store owner, Balbir Atwal, will receive the largest amount -- one-million-dollars (US).
He told people gathered outside his store how he plans to spend the money.
"First thing I will give to some charity and then I will be sharing with my own employees and with my family and friends," said Atwal.
A Florida retailer will receive 100-thousand dollars.
The owner of a food-mart in Munford, Tennessee, gets 25-thousand dollars.
Dana Naifeh says she hopes the winner linked to her store will contribute to the local community.
The Powerball payout was the largest lottery prize ever offered in North America.
No other lottery in the world has ever featured a jackpot of that size that could be won on a single ticket.
The winners have one year to claim their prize money.
