Cromwell is joined by four-time Belarusian national road champion Alena Amialiusik, former individual time trial world champion Lisa Brennauer, Italian sprinter Barbara Guarischi, German road race champion Mieke Kröger and young American rider Alexis Ryan.
"There's such a buzz around the city for these two weeks and it creates an incredible atmosphere to be part of," Cromwell said.
"We'll see that the tour is going to be a lot different compared to Australian nationals and I'm happy that there are another five Canyon SRAM teammates out on the road with me."
The four-day stage race starts with an undulating stage from Hahndorf to Meadows. The 106km stage with an 11 per cent steep Paris Creek QOM just 4km before the finish is set to clearly outline the GC contenders for the tour.
Stage 2, a circuit style race around the city centre in front of huge crowds is almost certain to finish in a bunch sprint. The remaining two stages, an undulating road stage in Tanunda and the Victoria Park criterium will see the overall finalised in what is predicted to be a tight battle with minimal time bonuses available throughout the tour.
Cromwell, who finished ninth in the Australian national road race on 9 January, said she is looking forward to the Santos Women's Tour.
"It's exciting to see a number of international teams who have come over to support the race and with the greater depth in the field to previous years," she said.
"Despite it still being very early in the season, I think we're going to see a dynamic and aggressive race that hopefully won't be dominated by just one team."